SCHEMBL1745447

SCHEMBL1745447

CCC(Oc1ccc(OC)cc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARG P37231 10/20 0.66
PPARA Q07869 10/20 0.66
SMN1; SMN2 Q16637 1/20 0.65
LDHA P00338 1/20 0.53
TAS1R3 Q7RTX0 1/20 0.51
TAS1R1 Q7RTX1 1/20 0.51
TAS1R2 Q8TE23 1/20 0.51
TSHR P16473 1/20 0.49
AKR1C3 P42330 3/20 0.47
AKR1C2 P52895 3/20 0.47
AKR1C1 Q04828 1/20 0.47
PTGS1 P23219 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16242008 1.00 PPARG (0.66) PPARGPPARASMN1; SMN2LDHATAS1R3
SCHEMBL21991991 1.00 PPARG (0.66) PPARGPPARASMN1; SMN2LDHATAS1R3
SCHEMBL9198747 0.89 PPARG (0.55) PPARGPPARASMN1; SMN2LDHATAS1R3
SCHEMBL7874488 0.88 PPARG (0.61) PPARGPPARASMN1; SMN2TSHRAKR1C3
SCHEMBL11550284 0.87 SMN1; SMN2 (0.67) PPARGPPARASMN1; SMN2
SCHEMBL13923928 0.86 PPARG (0.65) PPARGPPARASMN1; SMN2LDHATAS1R3
SCHEMBL9862303 0.86 TAS1R3 (0.62) PPARGPPARASMN1; SMN2LDHATAS1R3
SCHEMBL5011586 0.85 PTGS2 (0.54) PPARGPPARASMN1; SMN2
SCHEMBL11124599 0.85 PPARG (0.53) PPARGPPARASMN1; SMN2LDHATAS1R3
SCHEMBL8935859 0.85 SMN1; SMN2 (0.70) PPARGPPARASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070110844-A1 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. 2007-05-17 US claimed
EP-0159864-B1 METHOD OF MODIFYING TASTE TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1989-07-19 EP claimed
EP-0159864-A2 Method of modifying taste TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1985-10-30 EP claimed
EP-1971222-B1 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GEN MILLS INC (US) 2013-04-10 EP disclosed
US-20120037860-A1 DYE-CONTAINING NEGATIVE CURABLE COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2012-02-16 US disclosed
US-8057969-B2 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2011-11-15 US disclosed
US-8057969-B2 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2011-11-15 US disclosed
EP-2385032-A1 GPR40 Receptor function regulator Takeda Pharmaceutical Company Limited (JP) 2011-11-09 EP disclosed
US-8029951-B2 Colored curable composition, color filter and production method thereof FUJIFILM CORPORATION (JP) 2011-10-04 US disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-7575837-B2 Colored curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2009-08-18 US disclosed
US-7521158-B2 Negative dye-containing curable composition, color filter and method of producing the same FUJIFILM CORPORATION (JP) 2009-04-21 US disclosed
US-20080081268-A1 COLORED CURABLE COMPOSITION, COLOR FILTER AND PRODUCTION METHOD THEREOF FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed
US-20070254240-A1 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2007-11-01 US disclosed
US-20070254240-A1 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2007-11-01 US disclosed
US-20070110844-A1 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. 2007-05-17 US disclosed
US-5045336-A Reducing sweet taste of high sugar foods, organic acids and acid salts AMSTAR SUGAR CORPORATION (US) 1991-09-03 US disclosed
EP-0159864-B1 METHOD OF MODIFYING TASTE TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1989-07-19 EP disclosed
EP-0159864-A2 Method of modifying taste TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1985-10-30 EP disclosed