SCHEMBL914217

SCHEMBL914217

Cc1ccc(C(Oc2ccccc2)C(=O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.48
PPARA Q07869 3/20 0.48
CHRM1 P11229 1/20 0.48
KEAP1 Q14145 2/20 0.47
NFE2L2 Q16236 2/20 0.47
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
NPSR1 Q6W5P4 1/20 0.44
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
LMNA P02545 1/20 0.44
PKM P14618 2/20 0.43
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8935861 0.93 KDM4E (0.52) PPARGPPARACHRM1KEAP1NFE2L2
SCHEMBL8935862 0.93 KDM4E (0.52) PPARGPPARACHRM1KEAP1NFE2L2
SCHEMBL660871 0.87 KDM4E (0.55) PPARGPPARACHRM1KDM4EALDH1A1
SCHEMBL21881586 0.87 KDM4E (0.55) PPARGPPARACHRM1KDM4EALDH1A1
SCHEMBL13324879 0.87 KDM4E (0.55) PPARGPPARACHRM1KDM4EALDH1A1
SCHEMBL11577623 0.86 NPSR1 (0.52) PPARGPPARAALDH1A1NPSR1LMNA
SCHEMBL3773899 0.85 KDM4E (0.53) PPARGPPARAKDM4EALDH1A1NPSR1
Hydrogen Sulfide SCHEMBL28780976 0.85 KDM4E (0.54) PPARGPPARACHRM1KDM4EALDH1A1
SCHEMBL1564837 0.85 PPARG (0.44) PPARGPPARAKEAP1NFE2L2KDM4E
SCHEMBL1565656 0.85 LDHA (0.54) PPARGPPARAKEAP1NFE2L2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1616899-B2 Novel photoreactive polymers AGFA GRAPHICS NV (BE) 2014-07-02 EP disclosed
US-7905948-B2 Phase change ink compositions XEROX CORPORATION (US) 2011-03-15 US disclosed
US-7875698-B2 comprising dendritic polymer core of hyperbranched polyglycidol; for use in radiation curable varnishes, lacquers, printing inks, and inkjet inks AGFA GRAPHICS NV (BE) 2011-01-25 US disclosed
US-7795324-B2 Radiation curable compositions AGFA GRAPHICS, N.V. (BE) 2010-09-14 US disclosed
EP-1616899-B1 Novel photoreactive polymers AGFA GRAPHICS NV (BE) 2010-03-24 EP disclosed
EP-1674499-B1 Radiation curable compositions AGFA GRAPHICS NV (BE) 2009-12-16 EP disclosed
US-7538144-B2 Photoreactive polymers AGFA GRAPHICS, N.V. (BE) 2009-05-26 US disclosed
US-7507773-B2 Dendritic polymer core, e.g., hyperbranched polyglycidol, with at least one initiating functional group and at least one co-initiating functional group that is an aliphatic amine, an aromatic amine or a thiol; ink jet inks AGFA GRAPHICS N.V. (BE) 2009-03-24 US disclosed
US-20090046134-A1 Phase change ink compositions XEROX CORPORATION 2009-02-19 US disclosed
EP-1616920-B1 Novel polymeric initiators AGFA GRAPHICS NV (BE) 2008-02-20 EP disclosed
EP-1616921-B1 Novel radiation curable compositions AGFA GRAPHICS NV (BE) 2007-10-31 EP disclosed
EP-1674499-A1 Radiation curable compositions Agfa-Gevaert (BE) 2006-06-28 EP disclosed
US-20060014853-A1 Novel photoreactive polymers AGFA-GEVAERT (BE) 2006-01-19 US disclosed
US-20060014852-A1 Novel radiation curable compositions AGFA-GEVAERT (BE) 2006-01-19 US disclosed
US-20060014851-A1 Novel radiation curable compositions AGFA-GEVAERT (BE) 2006-01-19 US disclosed
US-20060014850-A1 Novel polymeric initiators AGFA-GEVAERT (BE) 2006-01-19 US disclosed
EP-1616921-A1 Novel radiation curable compositions Agfa-Gevaert (BE) 2006-01-18 EP disclosed
EP-1616920-A1 Novel polymeric initiators Agfa-Gevaert (BE) 2006-01-18 EP disclosed
EP-1616899-A1 Novel photoreactive polymers Agfa-Gevaert (BE) 2006-01-18 EP disclosed