Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267678 | 0.85 | GPR52 (0.48) | SCN5ASCN2AGPR52KDM4EALDH1A1 | |
| SCHEMBL8804035 | 0.79 | GPR52 (0.48) | SCN5ASCN2AMAPTGPR52KDM4E | |
| Naphthoic Acid SCHEMBL31550365 | 0.77 | CNR2 (0.49) | SCN5ASCN2AGPR52KDM4EALDH1A1 | |
| SCHEMBL5079813 | 0.76 | GPR52 (0.48) | SCN5ASCN2AMAPTGPR52KDM4E | |
| SCHEMBL7239901 | 0.74 | GPR52 (0.49) | SCN5ASCN2AMAPTGPR52KDM4E | |
| SCHEMBL20598171 | 0.73 | ALDH1A1 (0.55) | KDM4EALDH1A1CNR1ACHESIGMAR1 | |
| SCHEMBL7354117 | 0.72 | KDM4E (0.48) | MAPTGPR52KDM4EALDH1A1CNR1 | |
| SCHEMBL4948336 | 0.72 | GPR52 (0.50) | SCN5ASCN2AMAPTGPR52KDM4E | |
| SCHEMBL1000399 | 0.72 | KCNH2 (0.54) | MAPTRXFP1KDM4EALDH1A1ACHE | |
| SCHEMBL6423825 | 0.72 | CNR2 (0.51) | MAPTKDM4EALDH1A1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |