Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CATSPER1 | Q8NEC5 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936076 | 0.79 | GLA (0.44) | CA12CA2CA9CA1MAPT | |
| SCHEMBL11150237 | 0.72 | CATSPER1 (0.50) | CATSPER1CA12CA2CA9CA1 | |
| SCHEMBL3779883 | 0.71 | — | — | |
| SCHEMBL8785232 | 0.69 | CA12 (0.37) | CA12CA2CA9TBXA2RCA1 | |
| SCHEMBL8785818 | 0.68 | GLA (0.38) | CA12CA2CA9TBXA2RCA1 | |
| SCHEMBL31094691 | 0.68 | GLA (0.48) | CA12CA2CA9CA1MAPT | |
| SCHEMBL32691206 | 0.62 | CATSPER1 (0.40) | CATSPER1CA12CA2CA9MAPT | |
| SCHEMBL2207623 | 0.61 | MAPT (0.45) | CATSPER1CA12CA2CA9CA1 | |
| SCHEMBL11419688 | 0.60 | MAPT (0.47) | CATSPER1MAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL9213055 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1119013-A | Hydroxymethyl furazan carboxylic acid derivatives and their use in the treatment of cardiovascular disease | CASSELLA FARBWERKE MAINKUR AG (DE) | 1996-03-20 | — | — | CN | disclosed |
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |