Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25569896 | 0.87 | ATM (0.37) | NR1H2MEN1KMT2AATMPARP1 | |
| SCHEMBL19390106 | 0.86 | NR1H2 (0.39) | NR1H2MEN1KMT2AATMPARP1 | |
| SCHEMBL6183315 | 0.86 | HSD17B10 (0.35) | NR1H2MEN1KMT2AATMPARP1 | |
| SCHEMBL9696891 | 0.84 | MEN1 (0.34) | NR1H2MEN1KMT2AATMPARP1 | |
| SCHEMBL19390116 | 0.84 | ATM (0.41) | NR1H2MEN1KMT2AATMPARP1 | |
| SCHEMBL19074545 | 0.84 | MEN1 (0.34) | NR1H2MEN1KMT2AATMPARP1 | |
| SCHEMBL29280769 | 0.84 | MEN1 (0.34) | NR1H2MEN1KMT2AATMPARP1 | |
| SCHEMBL31048365 | 0.83 | NR1H2 (0.37) | NR1H2MEN1KMT2AATMSRC | |
| SCHEMBL584255 | 0.83 | NR1H2 (0.41) | NR1H2MEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL2839477 | 0.83 | NR1H2 (0.41) | NR1H2MEN1KMT2ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659178-A4 | CHIRAL QUINOLONE INTERMEDIATES. | ABBOTT LAB (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0659178-A1 | CHIRAL QUINOLONE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994006766-A1 | CHIRAL QUINOLONE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1994-03-31 | — | — | WO | disclosed |
| US-5252747-A | Chiral quinolone intermediates | ABBOTT LABORATORIES (US) | 1993-10-12 | — | — | US | disclosed |