Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19074545 | 1.00 | MEN1 (0.34) | MEN1KMT2ANR1H2ATMPARP1 | |
| SCHEMBL29280769 | 1.00 | MEN1 (0.34) | MEN1KMT2ANR1H2ATMPARP1 | |
| SCHEMBL12300133 | 0.88 | HSD11B1 (0.34) | MEN1KMT2ANR1H2ATMPARP1 | |
| SCHEMBL18700390 | 0.85 | ELANE (0.36) | MEN1KMT2AATMPARP1ELANE | |
| SCHEMBL25569896 | 0.84 | ATM (0.37) | MEN1KMT2ANR1H2ATMPARP1 | |
| SCHEMBL8936130 | 0.84 | NR1H2 (0.42) | MEN1KMT2ANR1H2ATMPARP1 | |
| SCHEMBL585407 | 0.84 | MEN1 (0.33) | MEN1KMT2ANR1H2ATMPARP1 | |
| SCHEMBL8936048 | 0.84 | HSD11B1 (0.36) | NR1H2ATMHSD11B1PTPN1 | |
| SCHEMBL585406 | 0.84 | MEN1 (0.33) | MEN1KMT2ANR1H2ATMPARP1 | |
| SCHEMBL6183315 | 0.83 | HSD17B10 (0.35) | MEN1KMT2ANR1H2ATMPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037367-A | Amino six-membered ring derivative and application thereof in medicines | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-11-11 | — | — | CN | disclosed |
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |