SCHEMBL6183315

SCHEMBL6183315

CC(C)(C)OC(=O)N1CC(=O)C[C@H]1CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.35
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
NR1H2 P55055 1/20 0.35
ATM Q13315 2/20 0.34
PARP1 P09874 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
HSD11B1 P28845 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8936130 0.86 NR1H2 (0.42) MEN1KMT2ANR1H2ATMPARP1
SCHEMBL25569896 0.86 ATM (0.37) MEN1KMT2ANR1H2ATMPARP1
SCHEMBL9696891 0.83 MEN1 (0.34) MEN1KMT2ANR1H2ATMPARP1
SCHEMBL29280769 0.83 MEN1 (0.34) MEN1KMT2ANR1H2ATMPARP1
SCHEMBL19074545 0.83 MEN1 (0.34) MEN1KMT2ANR1H2ATMPARP1
SCHEMBL13286306 0.81 CHRM2 (0.39) DDB1CRBNMEN1KMT2ANR1H2
SCHEMBL19152862 0.81 CHRM2 (0.39) DDB1CRBNMEN1KMT2ANR1H2
SCHEMBL12300133 0.81 HSD11B1 (0.34) MEN1KMT2ANR1H2ATMPARP1
SCHEMBL18700390 0.81 ELANE (0.36) MEN1KMT2AATMPARP1
SCHEMBL585407 0.80 MEN1 (0.33) MEN1KMT2ANR1H2ATMPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050256166-A1 Nitrogen-containing compounds ONO PHARMACEUTICAL CO., LTD. (JP) 2005-11-17 US disclosed
EP-1535906-A1 NITROGEN-CONTAINING COMPOUNDS ONO PHARMACEUTICAL CO., LTD. (JP) 2005-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050256166-A1 Nitrogen-containing compounds DPP4, DPP3, DPP8 HSD17B10 350/4885DDB1 601/4885CRBN 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.