Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 11/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587877 | 0.83 | HTR2A (0.46) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL8936189 | 0.82 | DRD2 (0.45) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL8665861 | 0.81 | DRD2 (0.44) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL8779094 | 0.75 | SIGMAR1 (0.57) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL14430319 | 0.73 | METAP1 (0.43) | DRD2HTR2AHTR2CSRD5A1SRD5A2 | |
| SCHEMBL29448019 | 0.73 | METAP1 (0.43) | DRD2HTR2AHTR2CSRD5A1SRD5A2 | |
| SCHEMBL9600590 | 0.72 | SRD5A1 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL8665382 | 0.72 | SRD5A1 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL8936164 | 0.72 | SMN1; SMN2 (0.41) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9600587 | 0.70 | SMN1; SMN2 (0.44) | DRD2HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514678-A | Arthropodicidal 1,2,4-triazinyl amides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-05-07 | — | — | US | disclosed |