SCHEMBL8936213

SCHEMBL8936213

CC(C)(C)S[C@@]1(C(=O)O)CCCN1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 1/20 0.32
ARG2 P78540 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8936209 1.00 ARG1 (0.32) ARG1ARG2
SCHEMBL7269187 0.79 ARG1 (0.34) ARG1ARG2
SCHEMBL7339201 0.74 ARG1 (0.35) ARG1ARG2
SCHEMBL9297313 0.74 ARG1 (0.35) ARG1ARG2
SCHEMBL7339204 0.74 ARG1 (0.35) ARG1ARG2
SCHEMBL18280875 0.74 AKR1C1 (0.34)
SCHEMBL18280876 0.70 ARG1 (0.35) ARG1ARG2
SCHEMBL6969192 0.69 ARG1 (0.35) ARG1ARG2
SCHEMBL5029633 0.68 TSHR (0.35) ARG1ARG2
SCHEMBL10986372 0.67 ARG1 (0.34) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510530-A WHEN POLYMERIZED GIVE OPTICALLY ACTIVE POLYMERS WHICH ARE USEFUL AS ADSORBENTS FOR CHROMATOGRAPHIC SEPARATION OF RACEMATES INTO ENANTIOMERS BAYER AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed
EP-0576949-B1 Optically active amino acid sulphoxide and sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatograpic separation of racemates BAYER AG (DE) 1996-01-31 EP disclosed
US-5481026-A ADDITION POLYMERIZABLE TO CHROMATOGRAPHIC SUPPORTS FOR SEPARATION OF RACEMIC MIXTURES BAYER AKTIENGESELLSCHAFT (DE) 1996-01-02 US disclosed
EP-0520242-B1 Optically active sulfur-containing aminoacid derivatives, their preparation, polymerisation into optically active polymers and use BAYER AG (DE) 1995-07-19 EP disclosed
US-5432252-A Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes BAYER AKTIENGESELLSCHAFT (DE) 1995-07-11 US disclosed
US-5432251-A Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes BAYER AKTIENGESELLSCHAFT (DE) 1995-07-11 US disclosed
US-5357001-A Optically active amino acid sulphoxide and amino acid sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatographic resolution of racemates BAYER AKTIENGESELLSCHAFT (DE) 1994-10-18 US disclosed
US-5347042-A Optically active sulphur-containing amino acid derivatives, their preparation, their polymerisation to give optically active polymers and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1994-09-13 US disclosed
EP-0576949-A1 Optically active amino acid sulphoxide and sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatograpic separation of racemates BAYER AG (DE) 1994-01-05 EP disclosed
EP-0520242-A1 Optically active sulfur-containing aminoacid derivatives, their preparation, polymerisation into optically active polymers and use BAYER AG (DE) 1992-12-30 EP disclosed