Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936213 | 0.79 | ARG1 (0.32) | ARG1ARG2 | |
| SCHEMBL7339204 | 0.79 | ARG1 (0.35) | ARG1ARG2 | |
| SCHEMBL9297313 | 0.79 | ARG1 (0.35) | ARG1ARG2 | |
| SCHEMBL8936209 | 0.79 | ARG1 (0.32) | ARG1ARG2 | |
| SCHEMBL7339201 | 0.79 | ARG1 (0.35) | ARG1ARG2 | |
| SCHEMBL18280876 | 0.75 | ARG1 (0.35) | ARG1ARG2 | |
| SCHEMBL6969192 | 0.73 | ARG1 (0.35) | ARG1ARG2 | |
| SCHEMBL5029633 | 0.72 | TSHR (0.35) | ARG1ARG2 | |
| SCHEMBL7339997 | 0.71 | — | — | |
| SCHEMBL7364415 | 0.71 | AKR1C1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422937-B1 | Fibrinogen receptor antagonists | MERCK & CO INC (US) | 1994-03-02 | — | — | EP | claimed |
| WO-1993000108-A1 | NOVEL INHIBITORS OF PLATELET AGGREGATION | CORVAS INTERNATIONAL, INC. (US) | 1993-01-07 | — | — | WO | claimed |
| US-5023233-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1991-06-11 | — | — | US | claimed |
| EP-0411833-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1991-02-06 | — | — | EP | claimed |
| EP-0410539-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1991-01-30 | — | — | EP | claimed |
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5583146-A | Heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0601459-A2 | Sulfonamido heterocyclic thrombin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |
| EP-0422937-B1 | Fibrinogen receptor antagonists | MERCK & CO INC (US) | 1994-03-02 | — | — | EP | disclosed |
| WO-1993016697-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1993-09-02 | — | — | WO | disclosed |
| US-5227490-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1993-07-13 | — | — | US | disclosed |
| US-5023233-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0411833-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1991-02-06 | — | — | EP | disclosed |
| EP-0052991-B1 | CARBOXYALKYL AMINO ACID DERIVATIVES OF VARIOUS SUBSTITUTED PROLINES | E.R. Squibb & Sons, Inc. (US) | 1987-02-04 | — | — | EP | disclosed |
| EP-0053902-B1 | PHOSPHINYLALKANOYL SUBSTITUTED PROLINES | E.R. Squibb & Sons, Inc. (US) | 1985-04-03 | — | — | EP | disclosed |
| US-4462943-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1984-07-31 | — | — | US | disclosed |
| EP-0053902-A1 | Phosphinylalkanoyl substituted prolines | E.R. Squibb & Sons, Inc. (US) | 1982-06-16 | — | — | EP | disclosed |
| EP-0052991-A1 | Carboxyalkyl amino acid derivatives of various substituted prolines | E.R. Squibb & Sons, Inc. (US) | 1982-06-02 | — | — | EP | disclosed |
| US-4316906-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |