Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936275 | 1.00 | ALOX5 (0.43) | ALOX5LCKFYNDAOPPARA | |
| SCHEMBL8247749 | 0.78 | DAO (0.39) | LCKDAOPTPN2PTPN1GPR35 | |
| SCHEMBL8936299 | 0.73 | ALOX5 (0.42) | ALOX5PPARAGUSBNR1H2TAS1R3 | |
| SCHEMBL8936295 | 0.73 | ALOX5 (0.42) | ALOX5PPARAGUSBNR1H2TAS1R3 | |
| SCHEMBL4210038 | 0.72 | ALOX5 (0.59) | ALOX5PPARAGUSBNR1H2TAS1R3 | |
| SCHEMBL4210041 | 0.72 | ALOX5 (0.59) | ALOX5PPARAGUSBNR1H2TAS1R3 | |
| SCHEMBL1493596 | 0.71 | PTPN2 (0.44) | PTPN2PTPN1GPR35AXLLMNA | |
| SCHEMBL1126746 | 0.70 | HCAR2 (0.54) | ALOX5PPARAGUSBTAS1R3TAS1R1 | |
| SCHEMBL12924107 | 0.70 | HCAR2 (0.54) | ALOX5PPARAGUSBTAS1R3TAS1R1 | |
| SCHEMBL1126747 | 0.70 | HCAR2 (0.54) | ALOX5PPARAGUSBTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031469-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |