SCHEMBL1126746

SCHEMBL1126746

O=C(O)/C=C/c1ccsc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.54
HDAC3 O15379 2/20 0.54
HDAC4 P56524 2/20 0.54
HDAC1 Q13547 2/20 0.54
HDAC7 Q8WUI4 2/20 0.54
HDAC2 Q92769 2/20 0.54
HDAC10 Q969S8 2/20 0.54
HDAC11 Q96DB2 2/20 0.54
HDAC8 Q9BY41 2/20 0.54
HDAC6 Q9UBN7 2/20 0.54
HDAC9 Q9UKV0 2/20 0.54
HDAC5 Q9UQL6 2/20 0.54
TNKS O95271 1/20 0.54
TNKS2 Q9H2K2 1/20 0.54
GUSB P08236 1/20 0.53
CA12 O43570 2/20 0.50
AKR1B10 O60218 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA3 P07451 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1126747 1.00 HCAR2 (0.54) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL12924107 1.00 HCAR2 (0.54) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL9257835 0.86 GUSB (0.45) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL9257838 0.86 GUSB (0.45) HCAR2HDAC3HDAC4HDAC1HDAC7
SCHEMBL9329946 0.85 GUSB (0.54) GUSBTAS1R3TAS1R1TYRALOX5
SCHEMBL9329953 0.85 GUSB (0.54) GUSBTAS1R3TAS1R1TYRALOX5
SCHEMBL20539212 0.84 GUSB (0.50) GUSBTAS1R3TAS1R1ALOX5JAK2
SCHEMBL20539210 0.84 GUSB (0.50) GUSBTAS1R3TAS1R1ALOX5JAK2
SCHEMBL9256644 0.82 GLA (0.53) GUSBTAS1R3TAS1R1ALOX5JAK2
SCHEMBL6836849 0.82 GUSB (0.51) GUSBTAS1R3TAS1R1ALOX5JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240276856-A1 PREPARATION METHOD OF LIGHT-EMITTING DEVICE, LIGHT-EMITTING DEVICE AND LIGHT-EMITTING APPARATUS Beijing Boe Technology Development Co., Ltd. (CN) 2024-08-15 US claimed
CN-116649008-A Preparation method of light-emitting device, light-emitting device and light-emitting device 京东方科技集团股份有限公司 2023-08-25 CN claimed
WO-2023115259-A1 MANUFACTURING METHOD FOR LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING DEVICE AND LIGHT-EMITTING APPARATUS 京东方科技集团股份有限公司 2023-06-29 WO claimed
CN-116003710-A Polyacrylic polymer modified substrate, preparation method thereof and application thereof in preparation of biochip 中国海洋大学 2023-04-25 CN claimed
CN-115986119-A Graphene conductive slurry premix and preparation method and application thereof 雅迪科技集团有限公司 2023-04-18 CN claimed
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME Alliance for Energy Innovation, LLC 2017-12-21 US claimed
US-20140086977-A1 TIGHT JUNCTIONS MODULATORS THE UNIVERSITY OF MANCHESTER (GB) 2014-03-27 US claimed
EP-2691090-A2 TIGHT JUNCTIONS MODULATORS The University Of Manchester (GB) 2014-02-05 EP claimed
WO-2012131341-A2 TIGHT JUNCTIONS MODULATORS THE UNIVERSITY OF MANCHESTER (GB) 2012-10-04 WO claimed
WO-2004061050-A1 COMPOSITION AND PROCESS FOR INHIBITING CORROSION OF METALLIC SUBSTRATES MACDERMID, INCORPORATED (US) 2004-07-22 WO claimed
US-6706214-B2 FOR PROVIDING CORROSION PROTECTION FOR ALUMINUM AND ALUMINUM ALLOYS CITIBANK, N.A. 2004-03-16 US claimed
EP-0688210-B1 USE OF CARNOSINE IN COMBINATION WITH UROCANIC ACID FOR TREATMENT OF PHOTODERMATOSES BEIERSDORF AG (DE) 2004-02-25 EP claimed
US-20030143420-A1 Composition and process for inhibiting corrosion of metallic substrates CITIBANK, N.A. 2003-07-31 US claimed
US-5995869-A Reduction of skin sensitization in electrotransport drug delivery ALZA CORPORATION (US) 1999-11-30 US claimed
WO-1997047355-A1 REDUCTION OF SKIN SENSITIZATION IN ELECTROTRANSPORT DRUG DELIVERY ALZA CORPORATION (US) 1997-12-18 WO claimed
US-12365830-B2 Ligand-exchangeable janus nanoparticles and methods of making the same ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2025-07-22 US disclosed
EP-4541178-A1 METHOD FOR INCREASING FLAVONOID CONTENT IN PLANT THROUGH TREATMENT WITH LOW-MOLECULAR-WEIGHT SULFUR COMPOUND Republic of Korea Management: Rural Development Administration (KR) 2025-04-23 EP disclosed
EP-0419410-A2 Alkanophenones CIBA-GEIGY AG (CH) 1991-03-27 EP disclosed
EP-0384450-A1 Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) 1990-08-29 EP disclosed
US-4093622-A Pyridine esters of cyclopropane-carboxylic acid ZOECON CORPORATION (US) 1978-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362255-A1 LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME CA6, CA13, EPCAM HCAR2 11/4885HDAC3 2613/4885HDAC4 2195/4885
US-20140086977-A1 TIGHT JUNCTIONS MODULATORS DSG1, KRT18, STOM HCAR2 41/4885HDAC3 3791/4885HDAC4 1854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.