SCHEMBL8936347

SCHEMBL8936347

O=C(O)C1CCCN(CCCN2c3ccccc3Sc3cncnc32)C1

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 3/20 0.63
DRD2 P14416 1/20 0.47
HRH1 P35367 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8936291 0.88 SLC6A1 (0.66) SLC6A1DRD2HRH1
SCHEMBL7607235 0.86 SLC6A1 (0.82) SLC6A1DRD2HRH1
SCHEMBL7607241 0.86 SLC6A1 (0.82) SLC6A1DRD2HRH1
Hydrochloric Acid SCHEMBL8195734 0.85 SLC6A1 (0.80) SLC6A1DRD2HRH1
Hydrochloric Acid SCHEMBL8195730 0.85 SLC6A1 (0.80) SLC6A1DRD2HRH1
SCHEMBL8936269 0.83 SLC6A1 (0.62) SLC6A1
SCHEMBL9084381 0.78 SLC6A1 (1.00) SLC6A1
SCHEMBL9084697 0.78 SLC6A1 (1.00) SLC6A1
SCHEMBL7608016 0.77 FPR2 (0.70) SLC6A1DRD2HRH1
SCHEMBL7608009 0.77 FPR2 (0.70) SLC6A1DRD2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996031469-A1 N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF NOVO NORDISK A/S (DK) 1996-10-10 WO claimed
WO-1996031469-A1 N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF NOVO NORDISK A/S (DK) 1996-10-10 WO disclosed