Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936565 | 0.92 | TACR1 (0.61) | TACR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8936431 | 0.91 | TACR1 (0.56) | TACR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8936446 | 0.85 | TACR1 (0.49) | TACR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8936556 | 0.84 | TACR1 (0.53) | TACR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8936575 | 0.83 | TACR1 (0.60) | TACR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8936460 | 0.82 | TACR1 (0.76) | TACR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8936514 | 0.80 | TACR1 (0.59) | TACR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8786193 | 0.76 | TACR1 (0.74) | TACR1NPC1MEN1KMT2ALMNA | |
| SCHEMBL8936536 | 0.74 | TACR1 (0.77) | TACR1NPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL8936580 | 0.74 | TACR1 (0.80) | TACR1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523305-A | ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0566069-A1 | Tachykinin receptor antagonists, isoquinolones and their production | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |