Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936431 | 0.89 | TACR1 (0.56) | TACR1THRBNPC1MEN1KMT2A | |
| SCHEMBL8936447 | 0.84 | TACR1 (0.53) | TACR1THRBNPC1MEN1KMT2A | |
| SCHEMBL8936446 | 0.84 | TACR1 (0.49) | TACR1NPC1MEN1KMT2ALMNA | |
| SCHEMBL8936575 | 0.83 | TACR1 (0.60) | TACR1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL8936514 | 0.80 | TACR1 (0.59) | TACR1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL8936460 | 0.78 | TACR1 (0.76) | TACR1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL8936565 | 0.78 | TACR1 (0.61) | TACR1THRBNPC1MEN1KMT2A | |
| SCHEMBL8936432 | 0.74 | TACR1 (0.74) | TACR1 | |
| SCHEMBL8786193 | 0.73 | TACR1 (0.74) | TACR1THRBNPC1MEN1KMT2A | |
| SCHEMBL8936601 | 0.72 | TACR1 (0.70) | TACR1NPC1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523305-A | ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-04 | — | — | US | disclosed |