Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 1.00 |
| ▸ | HPGD | P15428 | 7/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 5/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.60 |
| ▸ | TUBB | P07437 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Skimmianine SCHEMBL29594332 | 1.00 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDCYP3A4CYP1A2 | |
| Skimmianine SCHEMBL6933482 | 0.89 | ALDH1A1 (0.80) | ALDH1A1KDM4EHPGDCYP3A4CYP1A2 | |
| SCHEMBL15263337 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDCYP3A4CYP1A2 | |
| SCHEMBL29827080 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDCYP3A4CYP1A2 | |
| Gamma-Fagarine SCHEMBL679918 | 0.83 | KDM4E (1.00) | ALDH1A1KDM4EHPGDCYP3A4CYP1A2 | |
| Gamma-Fagarine SCHEMBL29594141 | 0.83 | KDM4E (1.00) | ALDH1A1KDM4EHPGDCYP3A4CYP1A2 | |
| SCHEMBL30071624 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDCYP3A4CYP1A2 | |
| SCHEMBL30645244 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCYP3A4CYP1A2 | |
| Evoxine SCHEMBL23870279 | 0.78 | KDM4E (1.00) | ALDH1A1KDM4EHPGDCYP3A4CYP1A2 | |
| Evoxine SCHEMBL30609974 | 0.78 | KDM4E (1.00) | ALDH1A1KDM4EHPGDCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109394870-B | Preparation method, content determination method and application of anticancer active site in cortex dictamni | 哈尔滨职业技术学院 | 2021-03-19 | — | — | CN | claimed |
| CN-110129150-A | One kind, which has, alleviates pruitus, beriberoid pyretic arthralgia, the Chinese medicine handmade soap and preparation method thereof of scabies sore leprosy symptom effect | 刘金钊 | 2019-08-16 | — | — | CN | claimed |
| EP-3500271-A1 | GENOME EDITING ENHANCERS | Bluebird Bio, Inc. (US) | 2019-06-26 | — | — | EP | claimed |
| US-20190169597-A1 | GENOME EDITING ENHANCERS | BLUEBIRD BIO, INC. (US) | 2019-06-06 | — | — | US | claimed |
| CN-109715171-A | Genome editor's enhancer | 蓝鸟生物公司 | 2019-05-03 | — | — | CN | claimed |
| CN-109394870-A | The preparation method at anticancer activity position, content assaying method and its application in cortex dictamni | 哈尔滨职业技术学院 | 2019-03-01 | — | — | CN | claimed |
| WO-2018035423-A1 | GENOME EDITING ENHANCERS | BLUEBIRD BIO, INC. (US) | 2018-02-22 | — | — | WO | claimed |
| CN-107629065-A | A kind of method of separation and concentration furoquinoline Alkaloid in skin from Dictamnus angustifolius | 中国药科大学 | 2018-01-26 | — | — | CN | claimed |
| CN-104738074-A | Plant antibiosis component-containing pesticide composition | WANG BAOYAN | 2015-07-01 | — | — | CN | claimed |
| EP-2665739-A1 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2013-11-27 | — | — | EP | claimed |
| CN-103360400-A | Salt for skimmianine derivates | SHANGHAI YIZHI MEDICAL TECH CO | 2013-10-23 | — | — | CN | claimed |
| US-20120302624-A1 | BIOMARKER FOR IDENTIFYING SUBGROUP OF EARLY-STAGE LUNG ADENOCARCINOMA PATIENTS | Lai jin-mei (TW) | 2012-11-29 | — | — | US | claimed |
| WO-2012100248-A1 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2012-07-26 | — | — | WO | claimed |
| US-20120114670-A1 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | UNIVERSITY OF ROCHESTER (US) | 2012-05-10 | — | — | US | claimed |
| US-20120082659-A1 | Methods And Compositions Related To Synergistic Responses To Oncogenic Mutations | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-05 | — | — | US | claimed |
| US-20100285001-A1 | Method and Compositions Related to Synergistic Responses to Oncogenic Mutations | UNIVERSITY OF ROCHESTER (US) | 2010-11-11 | — | — | US | claimed |
| EP-2188630-A2 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2010-05-26 | — | — | EP | claimed |
| WO-2009045443-A2 | METHODS AND COMPOSITIONS RELATED TO SYNERGISTIC RESPONSES TO ONCOGENIC MUTATIONS | THE UNIVERSITY OF ROCHESTER (US) | 2009-04-09 | — | — | WO | claimed |
| CN-1305742-A | Process for preparing Chinese Prickly ash flavouring by high-temp and high-pressure boiling in water | HANYUAN FOREIGN TRADE FOOD FAC (CN) | 2001-08-01 | — | — | CN | claimed |
| US-4767626-A | ALKALOID EXTRACT OF ZANTHOXYLUM SIMULANS | CHENG THEODORE (US) | 1988-08-30 | — | — | US | claimed |