Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 1.00 |
| ▸ | HPGD | P15428 | 9/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gamma-Fagarine SCHEMBL29594141 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Robustine SCHEMBL29351281 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Robustine SCHEMBL31419857 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Robustine SCHEMBL28488147 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Skimmianine SCHEMBL29594332 | 0.83 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Skimmianine SCHEMBL893654 | 0.83 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Skimmianine SCHEMBL6933482 | 0.80 | ALDH1A1 (0.80) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL31214315 | 0.79 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Dictamnine SCHEMBL1760700 | 0.76 | POLB (0.65) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL15263337 | 0.76 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229639-A1 | METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE | GBS Global Biopharma, Inc. (CA) | 2023-08-23 | — | — | EP | claimed |
| WO-2022081889-A1 | METHOD AND SYSTEMS FOR PHYTOMEDICINE ANALYTICS FOR RESEARCH OPTIMIZATION AT SCALE | GBS GLOBAL BIOPHARMA, INC. (CA) | 2022-04-21 | — | — | WO | claimed |
| EP-3500271-A1 | GENOME EDITING ENHANCERS | Bluebird Bio, Inc. (US) | 2019-06-26 | — | — | EP | claimed |
| US-20190169597-A1 | GENOME EDITING ENHANCERS | BLUEBIRD BIO, INC. (US) | 2019-06-06 | — | — | US | claimed |
| CN-109715171-A | Genome editor's enhancer | 蓝鸟生物公司 | 2019-05-03 | — | — | CN | claimed |
| CN-109394870-A | The preparation method at anticancer activity position, content assaying method and its application in cortex dictamni | 哈尔滨职业技术学院 | 2019-03-01 | — | — | CN | claimed |
| CN-106539804-B | A kind of molecule traditional Chinese medicine frostlike-powder and preparation method thereof for relief from osteoarthritis pain | 福建中医药大学 | 2018-12-21 | — | — | CN | claimed |
| CN-108354937-A | The new pharmaceutical uses of fagarine | 上海壹志医药科技有限公司 | 2018-08-03 | — | — | CN | claimed |
| WO-2018035423-A1 | GENOME EDITING ENHANCERS | BLUEBIRD BIO, INC. (US) | 2018-02-22 | — | — | WO | claimed |
| CN-107629065-A | A kind of method of separation and concentration furoquinoline Alkaloid in skin from Dictamnus angustifolius | 中国药科大学 | 2018-01-26 | — | — | CN | claimed |
| EP-2654727-A1 | METHODS OF PRODUCING STABILIZED SOLID DOSAGE PHARMACEUTICAL COMPOSITIONS CONTAINING MORPHINANS | Mallinckrodt LLC (US) | 2013-10-30 | — | — | EP | claimed |
| US-20130273153-A1 | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans | MNK 2011 LLC (F/K/A MALLINCKRODT INC.) | 2013-10-17 | — | — | US | claimed |
| WO-2012087377-A1 | METHODS OF PRODUCING STABILIZED SOLID DOSAGE PHARMACEUTICAL COMPOSITIONS CONTAINING MORPHINANS | MALLINCKRODT LLC (US) | 2012-06-28 | — | — | WO | claimed |
| US-20110287095-A1 | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans | Mallinkckrodt Inc. (US) | 2011-11-24 | — | — | US | claimed |
| WO-2011087765-A2 | METHODS OF PRODUCING STABILIZED SOLID PHARMACEUTICAL COMPOSITIONS CONTAINING MORPHINANS | MALLINCKRODT INC. (US) | 2011-07-21 | — | — | WO | claimed |
| US-20110150989-A1 | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans | Mallinkckrodt Inc. (US) | 2011-06-23 | — | — | US | claimed |
| WO-2011041470-A2 | SUSTAINED-RELEASE OPIATE AND OPIATE DERIVATIVE COMPOSITIONS | MALLINCKRODT INC. (US) | 2011-04-07 | — | — | WO | claimed |
| US-20110077222-A1 | Sustained-Release Opiate and Opiate Derivative Compositions | MALLINCKRODT INC. (US) | 2011-03-31 | — | — | US | claimed |
| EP-0496349-B1 | Coating solution for preventing adhesion of polymer scale and method for its use | SHINETSU CHEMICAL CO (JP) | 1996-04-10 | — | — | EP | claimed |
| US-4767626-A | ALKALOID EXTRACT OF ZANTHOXYLUM SIMULANS | CHENG THEODORE (US) | 1988-08-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110150989-A1 | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans | LPXN, FSCN1, NCLN | KDM4E 4729/4885ALDH1A1 3382/4885HPGD 1410/4885 |
| US-20110287095-A1 | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans | LPXN, FSCN1, NCLN | KDM4E 4729/4885ALDH1A1 3382/4885HPGD 1410/4885 |
| US-20110077222-A1 | Sustained-Release Opiate and Opiate Derivative Compositions | OPRL1, OPRK1, OPRM1 | KDM4E 3460/4885ALDH1A1 896/4885HPGD 767/4885 |
| US-20130273153-A1 | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans | LPXN, FSCN1, NCLN | KDM4E 4729/4885ALDH1A1 3382/4885HPGD 1410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.