Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 6/20 | 0.35 |
| ▸ | TK1 | P04183 | 2/20 | 0.34 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936590 | 1.00 | P2RY2 (0.42) | P2RY2BCHETYMSTOP2ATK1 | |
| SCHEMBL8936607 | 1.00 | P2RY2 (0.42) | P2RY2BCHETYMSTOP2ATK1 | |
| SCHEMBL25374524 | 0.85 | BCHE (0.50) | BCHETOP2ATK1RNASE1 | |
| SCHEMBL30481508 | 0.85 | BCHE (0.50) | BCHETOP2ATK1RNASE1 | |
| SCHEMBL9126273 | 0.85 | BCHE (0.50) | BCHETOP2ATK1RNASE1 | |
| SCHEMBL9126280 | 0.85 | BCHE (0.50) | BCHETOP2ATK1RNASE1 | |
| SCHEMBL9129020 | 0.79 | DUT (0.46) | P2RY2BCHE | |
| SCHEMBL9407407 | 0.79 | DUT (0.46) | P2RY2BCHE | |
| SCHEMBL9129024 | 0.79 | DUT (0.46) | P2RY2BCHE | |
| SCHEMBL8936683 | 0.78 | P2RY2 (0.53) | P2RY2TYMSRNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576429-A | HUMAN T-CELL LEUKEMIA/LYMPHOMA VIRICIDE; ANTITUMOR AGENT | MEDIVIR AB (SE) | 1996-11-19 | — | — | US | disclosed |
| WO-1989012061-A1 | PYRIMIDINE NUCLEOSIDES AND INTERMEDIATES | MEDIVIR AB (SE) | 1989-12-14 | — | — | WO | disclosed |