Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936638 | 0.86 | BRD4 (0.44) | SMN1; SMN2ALDH1A1CASP1PKMCASP7 | |
| SCHEMBL8936588 | 0.77 | MAPT (0.50) | SMN1; SMN2MAPTLMNAPOLBGAA | |
| SCHEMBL9101435 | 0.75 | TP53 (0.60) | SMN1; SMN2MAPTLMNAPOLBTP53 | |
| SCHEMBL9369130 | 0.74 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1CASP1PKMCASP7 | |
| SCHEMBL9368959 | 0.72 | AKT1 (0.47) | SMN1; SMN2ALDH1A1CASP1PKMCASP7 | |
| SCHEMBL9099840 | 0.72 | MAPT (0.58) | SMN1; SMN2MAPTLMNAPOLBGAA | |
| SCHEMBL8301100 | 0.70 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1CASP1PKMCASP7 | |
| SCHEMBL8791051 | 0.70 | BRD4 (0.51) | SMN1; SMN2ALDH1A1CASP1PKMCASP7 | |
| SCHEMBL9369777 | 0.69 | BRD4 (0.50) | SMN1; SMN2ALDH1A1CASP1PKMCASP7 | |
| SCHEMBL8301745 | 0.68 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1CASP1PKMCASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547951-A | ENZYME INHIBITORS; AIDS | BOEHRINGER INGELHEIM PHARAMCEUTICALS, INC. (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0417534-A1 | Pyrido[2,3-b][1,4]benzoxazepin (and thiazepin)-6(5H)-ones and thiones and their use in the prevention or treatment of AIDS | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1991-03-20 | — | — | EP | disclosed |