Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.75 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.67 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.64 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.64 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL30254944 | 0.93 | GPR84 (0.77) | CAMK2AGPR84FFAR1FFAR4LMNA | |
| Succinic Acid SCHEMBL1132170 | 0.93 | GPR84 (0.77) | CAMK2AGPR84FFAR1FFAR4LMNA | |
| Succinic Acid SCHEMBL27769216 | 0.91 | CAMK2A (0.63) | CAMK2AGPR84FFAR1FFAR4LMNA | |
| 1,3-Propanediol SCHEMBL29216017 | 0.90 | CAMK2A (0.71) | CAMK2AGPR84FFAR1FFAR4LMNA | |
| Adipic Acid SCHEMBL5448042 | 0.90 | GPR84 (0.82) | CAMK2AGPR84FFAR1FFAR4LMNA | |
| Adipic Acid SCHEMBL10993632 | 0.90 | GPR84 (0.82) | CAMK2AGPR84FFAR1FFAR4LMNA | |
| Succinic Acid SCHEMBL29958676 | 0.90 | GPR84 (0.82) | CAMK2AGPR84FFAR1FFAR4LMNA | |
| Succinic Acid SCHEMBL28369823 | 0.90 | CAMK2A (0.93) | CAMK2AGPR84FFAR1FFAR4LMNA | |
| Succinic Acid SCHEMBL1899650 | 0.90 | GPR84 (0.82) | CAMK2AGPR84FFAR1FFAR4LMNA | |
| Succinic Acid SCHEMBL28911181 | 0.90 | GPR84 (0.72) | CAMK2AGPR84FFAR1FFAR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119875069-A | Maleopimaric alcohol modified thermosetting polyurethane and preparation method thereof | 广西民族大学 | 2025-04-25 | — | — | CN | claimed |
| CN-117701217-A | Bio-based moisture-curable polyurethane hot melt adhesive and preparation method thereof | 烟台德邦科技股份有限公司 | 2024-03-15 | — | — | CN | claimed |
| WO-2022174333-A1 | BIOBASED COMPOSITIONS | Evoco Limited (CA) | 2022-08-25 | — | — | WO | claimed |
| WO-2022109723-A1 | POLYURETHANE ELASTOMER COMPOSITIONS, ARTICLES OF MANUFACTURE COMPRISING SAME, AND PROCESSES | Evoco Limited (CA) | 2022-06-02 | — | — | WO | claimed |
| CN-109438653-B | Biological thermoplastic polyurethane elastomer and preparation method thereof | 万华化学集团股份有限公司 | 2021-04-20 | — | — | CN | claimed |
| CN-107760014-B | Solvent-resistant thermoplastic polyurethane elastomer and preparation method thereof | 山东一诺威聚氨酯股份有限公司 | 2021-03-26 | — | — | CN | claimed |
| EP-3356455-A1 | HIGH PERFORMANCE COATINGS | Resinate Materials Group, Inc. (US) | 2018-08-08 | — | — | EP | claimed |
| CN-119978973-A | Thermosetting bio-based polyurethane antibacterial powder coating and preparation method thereof | 广西民族大学 | 2025-05-13 | — | — | CN | disclosed |
| CN-119875069-A | Maleopimaric alcohol modified thermosetting polyurethane and preparation method thereof | 广西民族大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-119875070-A | Rosin derivative modified thermosetting bio-based polyurethane and preparation method thereof | 广西民族大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-119875068-A | Propylene pimaric alcohol modified thermoplastic polyurethane and preparation method thereof | 广西民族大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-117701217-A | Bio-based moisture-curable polyurethane hot melt adhesive and preparation method thereof | 烟台德邦科技股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| US-11787918-B2 | Biobased compositions | Evoco Limited (CA) | 2023-10-17 | — | — | US | disclosed |
| EP-3356455-A1 | HIGH PERFORMANCE COATINGS | Resinate Materials Group, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| US-20170096581-A1 | HIGH PERFORMANCE COATINGS | RESINATE MATERIALS GROUP, INC. | 2017-04-06 | — | — | US | disclosed |
| EP-2793551-A1 | PLANT ARTIFICIAL SEEDS AND METHODS FOR THE PRODUCTION THEREOF | E. I. Du Pont de Nemours and Company (US) | 2014-10-29 | — | — | EP | disclosed |
| US-20130174483-A1 | PLANT ARTIFICIAL SEEDS AND METHODS FOR THE PRODUCTION THEREOF | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-07-11 | — | — | US | disclosed |
| WO-2013096531-A1 | PLANT ARTIFICIAL SEEDS AND METHODS FOR THE PRODUCTION THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-27 | — | — | WO | disclosed |
| EP-2607428-A1 | RESIN COMPOSITION | Kao Corporation (JP) | 2013-06-26 | — | — | EP | disclosed |
| US-5545681-A | pH-Modified polymer compositions with enhanced biodegradability | THE PROCTER & GAMBLE COMPANY (US) | 1996-08-13 | — | — | US | disclosed |