SCHEMBL8936684

SCHEMBL8936684

O=c1cc[nH]c2cc3ccccc3n12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.44
PARP1 P09874 1/20 0.36
CA12 O43570 1/20 0.35
BRD4 O60885 1/20 0.35
BRPF1 P55201 1/20 0.35
CA9 Q16790 1/20 0.35
KAT2B Q92831 1/20 0.35
BRD9 Q9H8M2 1/20 0.35
DAO P14920 2/20 0.35
NOTUM Q6P988 2/20 0.35
GAA P10253 2/20 0.35
PKM P14618 2/20 0.35
HSD17B10 Q99714 2/20 0.35
CASP1 P29466 1/20 0.35
GALK1 P51570 1/20 0.35
BLM P54132 1/20 0.35
CASP7 P55210 1/20 0.35
KMT2A Q03164 1/20 0.35
SAE1 Q9UBE0 1/20 0.35
UBA2 Q9UBT2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7439478 0.70 MAPK8 (0.43) CDC25BPARP1CA12BRD4BRPF1
SCHEMBL38660783 0.70 DAO (0.47) CDC25BCA12BRD4BRPF1CA9
SCHEMBL29412453 0.69 HSD17B10 (0.49) CDC25BCA12BRD4BRPF1CA9
SCHEMBL11572361 0.69 HSD17B10 (0.49) CDC25BCA12BRD4BRPF1CA9
SCHEMBL22766049 0.68 CDC25B (0.37) CDC25BDAONOTUMHSD17B10KMT2A
SCHEMBL29754258 0.68 CDC25B (0.77) CDC25BCA12CA9GAAPKM
SCHEMBL12324447 0.67 GAA (0.51) CDC25BPARP1DAONOTUMGAA
SCHEMBL22045317 0.67 CDC25B (0.54) CDC25BPARP1GAACASP7KDM4E
SCHEMBL10919955 0.67 MAPK1 (0.37) CDC25BCA12BRD4BRPF1CA9
SCHEMBL24428883 0.66 CDC25B (0.45) CDC25BPARP1DAONOTUMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5576432-A Process for the manufacture of dihydropyrimidines EASTMAN KODAK COMPANY (US) 1996-11-19 US disclosed