Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198771 | 0.90 | PKM (0.41) | PKMCYP19A1HTR2ASLC6A4MAPT | |
| SCHEMBL9196269 | 0.89 | CYP19A1 (0.43) | PKMCYP19A1HTR2ASLC6A4MAPT | |
| SCHEMBL9201983 | 0.88 | PKM (0.41) | PKMCYP19A1MAPTKMT2AALDH1A1 | |
| SCHEMBL8936755 | 0.88 | PKM (0.41) | PKMCYP19A1HTR2ASLC6A4MAPT | |
| SCHEMBL8936771 | 0.88 | TDP1 (0.41) | PKMCYP19A1HTR2ASLC6A4MAPT | |
| SCHEMBL9201309 | 0.88 | CCR1 (0.45) | PKMCYP19A1HTR2ASLC6A4MAPT | |
| SCHEMBL9202877 | 0.86 | PKM (0.40) | PKMCYP19A1SLC6A4CYP1A2CYP2C9 | |
| SCHEMBL8936739 | 0.85 | MEN1 (0.40) | PKMHTR2ASLC6A4MAPTKMT2A | |
| SCHEMBL8936766 | 0.79 | MAPT (0.41) | PKMCYP19A1HTR2ASLC6A4MAPT | |
| SCHEMBL8936735 | 0.72 | PDE7A (0.45) | PKMCYP19A1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |