Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936786 | 0.93 | GABRA1 (0.32) | — | |
| SCHEMBL8938052 | 0.93 | NAAA (0.35) | NAAAKDM1AFGFR2FGFR1 | |
| SCHEMBL8936825 | 0.92 | CCNT1 (0.32) | — | |
| SCHEMBL8936745 | 0.91 | RARB (0.31) | — | |
| SCHEMBL8936866 | 0.91 | RARB (0.33) | — | |
| SCHEMBL8936819 | 0.91 | RARB (0.33) | — | |
| SCHEMBL8936814 | 0.91 | RARB (0.33) | — | |
| SCHEMBL8936787 | 0.91 | RARB (0.33) | — | |
| SCHEMBL8964636 | 0.91 | NAAA (0.31) | NAAA | |
| SCHEMBL8939204 | 0.91 | FGFR1 (0.31) | FGFR2FGFR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |