Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550935 | 0.81 | PPARG (0.51) | HTTMAPTLMNASLC6A4HTR2A | |
| SCHEMBL4448137 | 0.79 | SLC6A4 (0.53) | MAPTSLC6A4HTR2AKCNH2SLC6A2 | |
| SCHEMBL8936781 | 0.78 | ESRRA (0.43) | HTTMAPTLMNASLC6A4KCNH2 | |
| SCHEMBL8936827 | 0.76 | HTT (0.67) | HTTMAPTLMNASLC6A4CYP2A6 | |
| SCHEMBL9194951 | 0.74 | FNTA (0.56) | HTTMAPTLMNAMEN1KMT2A | |
| SCHEMBL6783620 | 0.73 | L3MBTL1 (0.55) | HTTMAPTLMNAGAAMEN1 | |
| SCHEMBL5660028 | 0.73 | CYP1A2 (0.53) | HTTSLC6A4CYP2A6HTR2AKCNH2 | |
| SCHEMBL25101080 | 0.72 | HTT (0.57) | HTTMAPTLMNASLC6A4CYP2A6 | |
| SCHEMBL3155165 | 0.72 | GAA (0.56) | HTTMAPTLMNASLC6A4CYP2A6 | |
| SCHEMBL30207438 | 0.72 | HTT (0.57) | HTTMAPTLMNASLC6A4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |