Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | PARG | Q86W56 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13749562 | 0.82 | CYP1A2 (0.62) | LMNAMAPTSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10702984 | 0.82 | CYP1A2 (0.58) | MAPTSLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL28286771 | 0.80 | GAA (0.57) | HTTLMNAMAPTPARGSLC6A4 | |
| SCHEMBL807773 | 0.78 | SLC6A2 (0.59) | LMNAMAPTSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13997359 | 0.78 | L3MBTL1 (0.47) | HTTLMNAMAPTPARGSLC6A4 | |
| SCHEMBL10828212 | 0.77 | CYP1A2 (0.49) | LMNAMAPTSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4441083 | 0.77 | SLC6A2 (0.64) | MAPTSLC6A4SLC6A2SLC6A3L3MBTL1 | |
| SCHEMBL8936811 | 0.76 | HTT (0.61) | HTTLMNAMAPTPARGSLC6A4 | |
| SCHEMBL10828216 | 0.76 | MEN1 (0.47) | MAPTSLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL20565912 | 0.76 | MAOA (0.57) | HTTLMNAMAPTSLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |