Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936903 | 0.92 | TACR1 (0.39) | TACR1GPBAR1SLC1A5MMEACE | |
| SCHEMBL8936931 | 0.73 | TACR1 (0.40) | TACR1 | |
| SCHEMBL8936871 | 0.73 | TACR1 (0.45) | TACR1 | |
| SCHEMBL8936863 | 0.71 | TACR1 (0.45) | TACR1 | |
| SCHEMBL8936826 | 0.70 | TACR1 (0.61) | TACR1 | |
| SCHEMBL8936832 | 0.70 | TACR1 (0.61) | TACR1 | |
| SCHEMBL8936828 | 0.66 | TACR1 (0.38) | TACR1PTPN1 | |
| SCHEMBL8936907 | 0.66 | TACR1 (0.64) | TACR1 | |
| SCHEMBL8936904 | 0.66 | TACR1 (0.63) | TACR1 | |
| SCHEMBL5793298 | 0.65 | MAPT (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494926-A | ANTIINFLAMMATORY AGENT, ANTIARTHRITIC AGENT; TREATING PAIN, HEADACHE | MERCK SHARP & DOHME LTD. (GB) | 1996-02-27 | — | — | US | disclosed |