Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936863 | 0.91 | TACR1 (0.45) | TACR1 | |
| SCHEMBL8936912 | 0.80 | TACR1 (0.43) | TACR1 | |
| SCHEMBL8936871 | 0.76 | TACR1 (0.45) | TACR1 | |
| SCHEMBL8936826 | 0.75 | TACR1 (0.61) | TACR1 | |
| SCHEMBL8936832 | 0.75 | TACR1 (0.61) | TACR1 | |
| SCHEMBL8936909 | 0.73 | TACR1 (0.38) | TACR1 | |
| SCHEMBL8936906 | 0.71 | TRPV6 (0.42) | TACR1 | |
| SCHEMBL8936903 | 0.70 | TACR1 (0.39) | TACR1 | |
| SCHEMBL8936907 | 0.70 | TACR1 (0.64) | TACR1 | |
| SCHEMBL8936904 | 0.70 | TACR1 (0.63) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494926-A | ANTIINFLAMMATORY AGENT, ANTIARTHRITIC AGENT; TREATING PAIN, HEADACHE | MERCK SHARP & DOHME LTD. (GB) | 1996-02-27 | — | — | US | claimed |
| WO-1993024465-A1 | 2/3-(HETEROCYCLIC ALKYL AMINO)-1-(SUBST.-PHENYL-METHOXY)-ETHANES/PROPANES AS TACHYKININ-RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1993-12-09 | — | — | WO | claimed |