SCHEMBL8936941

SCHEMBL8936941

C/C=C/CCC1CC=C(c2ccc(-c3ccc(-c4ccc(OCCCC)c(F)c4F)cc3)c(F)c2)CC1

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTGES O14684 1/20 0.30
ALOX5 P09917 1/20 0.30
ESR2 Q92731 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30
CCNT1 O60563 1/20 0.30
CDK9 P50750 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8936945 0.97
SCHEMBL8936957 0.97 RARB (0.31)
SCHEMBL8937019 0.97 RARB (0.31)
SCHEMBL8936954 0.97 RARB (0.31)
SCHEMBL8936977 0.97 RARB (0.31)
SCHEMBL8936943 0.96 FFAR4 (0.31) ESR2FFAR4
SCHEMBL8938175 0.94 RARA (0.31) PTGESALOX5
SCHEMBL8936929 0.93 PDE5A (0.32) ESR2CCNT1CDK9
SCHEMBL8938177 0.92
SCHEMBL8964902 0.91 PTGES (0.30) PTGESALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed