Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 12/20 | 0.48 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936975 | 1.00 | MAPK8 (0.48) | MAPK8MAPK9MAPK10RENKDM1A | |
| SCHEMBL8937022 | 0.88 | CAPN1 (0.49) | CAPN1 | |
| SCHEMBL8937016 | 0.88 | CAPN1 (0.49) | CAPN1 | |
| SCHEMBL30525421 | 0.88 | CAPN1 (0.50) | CAPN1 | |
| SCHEMBL38663940 | 0.87 | REN (0.56) | MAPK8MAPK9MAPK10RENKDM1A | |
| SCHEMBL30067104 | 0.86 | PTPN1 (0.48) | CAPN1 | |
| SCHEMBL30199670 | 0.86 | MAPK8 (0.46) | MAPK8MAPK9MAPK10RENKDM1A | |
| SCHEMBL29607747 | 0.85 | REN (0.54) | MAPK8MAPK9MAPK10RENCAPN1 | |
| SCHEMBL30666371 | 0.84 | CAPN1 (0.53) | CAPN1 | |
| SCHEMBL30020318 | 0.84 | MAPK8 (0.53) | MAPK8MAPK9MAPK10RENKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673384-A4 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS. | UNIV MINNESOTA (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0673384-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1994013692-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-06-23 | — | — | WO | claimed |