Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 4/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 3/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CALCR | P30988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31757091 | 0.95 | CAPN1 (0.50) | MAPK8MAPK9MAPK10F2KEAP1 | |
| SCHEMBL29390993 | 0.87 | F2 (0.51) | F2NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL29756030 | 0.85 | NTSR1 (0.50) | F2CAPN1NPY2RNPY4RNPY5R | |
| SCHEMBL8936975 | 0.84 | MAPK8 (0.48) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL8936981 | 0.84 | MAPK8 (0.48) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL30980911 | 0.82 | MAPK8 (0.63) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL30199670 | 0.81 | MAPK8 (0.46) | MAPK8MAPK9MAPK10F2KEAP1 | |
| SCHEMBL30432915 | 0.81 | CALCRL (0.50) | F2NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL29607747 | 0.80 | REN (0.54) | MAPK8MAPK9MAPK10CAPN1REN | |
| SCHEMBL38659950 | 0.80 | CALCRL (0.43) | KEAP1KDM1ACAPN1MAOBKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032850-B | Oligomeric particle reagents and methods of use thereof | 朱诺治疗学有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-117106716-A | Method for culturing cells and kit and device for use in the method | 朱诺治疗学有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116875635-A | Method, reagent cartridge, reagent and device for transduction | 朱诺治疗学有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116656605-A | Methods, kits and devices for expanding cell populations | 朱诺治疗有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-108474002-B | Method, reagent cartridge, reagent and device for transduction | 朱诺治疗学有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-108431210-B | Method for culturing cells and kit and device for use in the method | 朱诺治疗学有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-115261317-A | Method for culturing cells, and kit and apparatus for the same | 朱诺治疗学有限公司 | 2022-11-01 | — | — | CN | disclosed |