Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 11/20 | 0.51 |
| ▸ | NTSR2 | O95665 | 8/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936991 | 1.00 | XIAP (0.51) | XIAPNTSR1NTSR2SORT1OPRD1 | |
| SCHEMBL29601866 | 0.90 | OPRM1 (0.51) | NTSR1NTSR2SORT1OPRD1OPRM1 | |
| SCHEMBL31257010 | 0.85 | XIAP (0.57) | XIAPNTSR1NTSR2SORT1REN | |
| SCHEMBL29612048 | 0.85 | NTSR1 (0.49) | XIAPNTSR1NTSR2SORT1OPRD1 | |
| SCHEMBL29801939 | 0.85 | ACE (0.50) | XIAPNTSR1NTSR2SORT1OPRM1 | |
| SCHEMBL29611519 | 0.84 | NTSR1 (0.51) | XIAPNTSR1NTSR2SORT1OPRD1 | |
| SCHEMBL29677036 | 0.84 | OPRM1 (0.48) | NTSR1NTSR2SORT1OPRD1OPRM1 | |
| SCHEMBL31447608 | 0.84 | F2 (0.52) | XIAPNTSR1NTSR2SORT1OPRD1 | |
| SCHEMBL13697491 | 0.84 | NPY2R (0.46) | XIAPNTSR1NTSR2SORT1 | |
| SCHEMBL29612063 | 0.83 | NTSR1 (0.49) | NTSR1NTSR2SORT1OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673384-A4 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS. | UNIV MINNESOTA (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0673384-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013692-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-06-23 | — | — | WO | disclosed |