Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 9/20 | 0.46 |
| ▸ | FNTB | P49356 | 9/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8936984 | 0.99 | TAS1R3 (0.46) | TAS1R3TAS1R1FNTAFNTBL3MBTL1 | |
| SCHEMBL8936950 | 0.97 | FNTA (0.45) | TAS1R3TAS1R1FNTAFNTBL3MBTL1 | |
| SCHEMBL8367864 | 0.91 | FNTA (0.49) | FNTAFNTB | |
| Hydrochloric Acid SCHEMBL8366423 | 0.91 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL9005958 | 0.90 | FNTA (0.50) | TAS1R3TAS1R1FNTAFNTBL3MBTL1 | |
| SCHEMBL8369462 | 0.90 | FNTA (0.50) | TAS1R3TAS1R1FNTAFNTBL3MBTL1 | |
| SCHEMBL9005974 | 0.81 | FNTA (0.54) | FNTAFNTB | |
| SCHEMBL8367856 | 0.81 | FNTA (0.54) | FNTAFNTB | |
| SCHEMBL8937032 | 0.80 | FNTA (0.59) | TAS1R3TAS1R1FNTAFNTBL3MBTL1 | |
| SCHEMBL8995686 | 0.80 | FNTA (0.58) | TAS1R3TAS1R1FNTAFNTBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030015-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | claimed |
| US-5534537-A | Prodrugs of inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1996-07-09 | — | — | US | claimed |
| US-5578629-A | ANTICARCINOGENIC AGENTS | MERCK & CO., INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5534537-A | Prodrugs of inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1996-07-09 | — | — | US | disclosed |