Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | RAMP3 | O60896 | 11/20 | 0.43 |
| ▸ | CALCR | P30988 | 11/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937042 | 1.00 | MAPK8 (0.50) | MAPK8MAPK9MAPK10EPHA2KDM1A | |
| SCHEMBL8697957 | 0.85 | CAPN1 (0.48) | EPHA2RAMP3CALCRCALCRL | |
| SCHEMBL8697990 | 0.85 | CAPN1 (0.48) | EPHA2RAMP3CALCRCALCRL | |
| SCHEMBL30522057 | 0.85 | KDM1A (0.52) | MAPK8MAPK9MAPK10EPHA2KDM1A | |
| SCHEMBL31410825 | 0.84 | MAPK8 (0.56) | MAPK8MAPK9MAPK10KDM1ARAMP3 | |
| SCHEMBL7163251 | 0.83 | MAPK8 (0.40) | MAPK8MAPK9MAPK10EPHA2KDM1A | |
| SCHEMBL7163247 | 0.83 | MAPK8 (0.40) | MAPK8MAPK9MAPK10EPHA2KDM1A | |
| SCHEMBL30844290 | 0.82 | KDM1A (0.56) | MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL28758609 | 0.82 | REN (0.44) | MAPK8MAPK9MAPK10KDM1A | |
| SCHEMBL30844398 | 0.82 | MAPK8 (0.54) | MAPK8MAPK9MAPK10EPHA2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673384-A4 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS. | UNIV MINNESOTA (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0673384-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1994013692-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-06-23 | — | — | WO | claimed |