Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.48 |
| ▸ | RAMP3 | O60896 | 12/20 | 0.47 |
| ▸ | CALCR | P30988 | 12/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.47 |
| ▸ | GRB2 | P62993 | 1/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697957 | 1.00 | CAPN1 (0.48) | CAPN1RAMP3CALCREPHA2GRB2 | |
| SCHEMBL31031563 | 0.95 | RAMP3 (0.49) | CAPN1RAMP3CALCREPHA2GRB2 | |
| SCHEMBL31265322 | 0.91 | EPHA2 (0.50) | RAMP3CALCREPHA2GRB2CALCRL | |
| SCHEMBL30676238 | 0.88 | EPHA2 (0.46) | CAPN1RAMP3CALCREPHA2GRB2 | |
| SCHEMBL29636364 | 0.86 | EPHA2 (0.51) | RAMP3CALCREPHA2GRB2 | |
| SCHEMBL29636362 | 0.86 | EPHA2 (0.51) | RAMP3CALCREPHA2GRB2 | |
| SCHEMBL8937033 | 0.85 | MAPK8 (0.50) | RAMP3CALCREPHA2CALCRL | |
| SCHEMBL8937042 | 0.85 | MAPK8 (0.50) | RAMP3CALCREPHA2CALCRL | |
| SCHEMBL29886811 | 0.85 | EPHA2 (0.45) | RAMP3CALCREPHA2GRB2CALCRL | |
| SCHEMBL31031612 | 0.85 | MAPK8 (0.54) | CAPN1RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840691-A | ADMINISTERING TO SUPPRESS INFLAMMATION, INHIBIT INFILTRATION OF LEUKOCYTES INTO TISSUE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1998-11-24 | — | — | US | claimed |
| US-5591719-A | TREATMENT OF ARTHRITIS, BLOCKING LEUKOCYTE ADHESION TO EPITHELIAL CELLS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1997-01-07 | — | — | US | claimed |
| EP-0673384-A4 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS. | UNIV MINNESOTA (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0673384-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1994013692-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-06-23 | — | — | WO | claimed |
| US-5294551-A | Heparin binders; adhesion promoters; oligopeptides | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-03-15 | — | — | US | claimed |
| US-5171271-A | Polypeptides with fibronectin activity | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1992-12-15 | — | — | US | claimed |
| US-5019646-A | Polypeptides with fibronectin activity | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1991-05-28 | — | — | US | claimed |
| EP-0366728-A1 | POLYPEPTIDES WITH FIBRONECTIN ACTIVITY. | UNIV MINNESOTA (US) | 1990-05-09 | — | — | EP | claimed |
| WO-1989001942-A1 | POLYPEPTIDES WITH FIBRONECTIN ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-03-09 | — | — | WO | claimed |
| US-5294551-A | Heparin binders; adhesion promoters; oligopeptides | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0366728-B1 | POLYPEPTIDES WITH FIBRONECTIN ACTIVITY | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1993-04-07 | — | — | EP | disclosed |
| US-5171271-A | Polypeptides with fibronectin activity | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1992-12-15 | — | — | US | disclosed |
| US-5019646-A | Polypeptides with fibronectin activity | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0366728-A1 | POLYPEPTIDES WITH FIBRONECTIN ACTIVITY. | UNIV MINNESOTA (US) | 1990-05-09 | — | — | EP | disclosed |
| WO-1989001942-A1 | POLYPEPTIDES WITH FIBRONECTIN ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-03-09 | — | — | WO | disclosed |