Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 8/20 | 0.56 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CTSH | P09668 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.54 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073467 | 0.94 | TACR1 (0.54) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL3089689 | 0.93 | CXCR4 (0.57) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL3089699 | 0.93 | CXCR4 (0.57) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL29463731 | 0.90 | CXCR4 (0.58) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL38651161 | 0.89 | CXCR4 (0.56) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL29845416 | 0.88 | KISS1R (0.57) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL30381291 | 0.88 | KISS1R (0.56) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL30597309 | 0.88 | DPP3 (0.57) | CXCR4CTSLCTSSCTSKCTSH | |
| SCHEMBL31668913 | 0.87 | C5AR1 (0.61) | CXCR4TACR1C5AR1 | |
| SCHEMBL31725194 | 0.87 | CTSL (0.63) | CXCR4CTSLCTSSCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673384-A4 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS. | UNIV MINNESOTA (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0673384-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1994013692-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-06-23 | — | — | WO | claimed |