Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937407 | 1.00 | LMNA (0.57) | LMNAALDH1A1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL8937402 | 1.00 | LMNA (0.57) | LMNAALDH1A1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL8937488 | 0.85 | ALDH1A1 (0.60) | LMNAALDH1A1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL8937491 | 0.85 | ALDH1A1 (0.60) | LMNAALDH1A1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL8937486 | 0.85 | ALDH1A1 (0.60) | LMNAALDH1A1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL11296725 | 0.78 | ALDH1A1 (0.54) | LMNAALDH1A1SMN1; SMN2KDM4ERELA | |
| SCHEMBL11891940 | 0.78 | ALDH1A1 (0.54) | LMNAALDH1A1SMN1; SMN2KDM4ERELA | |
| SCHEMBL11296722 | 0.78 | ALDH1A1 (0.54) | LMNAALDH1A1SMN1; SMN2KDM4ERELA | |
| SCHEMBL8937333 | 0.77 | MAOB (0.48) | LMNAALDH1A1MAPK1L3MBTL1MAOB | |
| SCHEMBL8937340 | 0.77 | MAOB (0.48) | LMNAALDH1A1MAPK1L3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559109-A | Method of treating a PAF-mediated pathology or for treating or preventing psoriasis, nephritis, asthma or shock by administering a PAF antagonist | SANKKO COMPANY, LIMITED (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5556852-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| US-5369106-A | N-acryloylpiperazine derivatives, their preparation and their use of PAF antagonists | SANKYO COMPANY, LIMITED (JP) | 1994-11-29 | — | — | US | disclosed |
| US-5192766-A | Platelet activating factor antagonist | SANKYO COMPANY, LIMITED (JP) | 1993-03-09 | — | — | US | disclosed |