Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.34 |
| ▸ | MGLL | Q99685 | 4/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.33 |
| ▸ | CDK9 | P50750 | 4/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | FSHR | P23945 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937869 | 0.99 | MGLL (0.35) | NAAAMGLLCCNT1CDK9TDP2 | |
| SCHEMBL8936247 | 0.93 | ESR2 (0.34) | NAAAMGLLCCNT1CDK9ESR2 | |
| SCHEMBL8937308 | 0.93 | NAAA (0.36) | NAAACCNT1CDK9TDP2ESR2 | |
| SCHEMBL8936340 | 0.92 | MGLL (0.33) | NAAAMGLLCCNT1CDK9ESR2 | |
| SCHEMBL8932609 | 0.92 | NAAA (0.34) | NAAAESR2 | |
| SCHEMBL8938930 | 0.92 | ESR2 (0.34) | CCNT1CDK9ESR2 | |
| SCHEMBL8937612 | 0.91 | RARB (0.33) | CCNT1CDK9ESR2 | |
| SCHEMBL8937875 | 0.91 | NAAA (0.33) | NAAAESR2 | |
| SCHEMBL8937588 | 0.91 | PTPN11 (0.32) | CCNT1CDK9ESR2 | |
| SCHEMBL8938966 | 0.91 | ESR2 (0.34) | MGLLCCNT1CDK9ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |