Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3805078 | 0.66 | ESR1 (0.41) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL8923831 | 0.64 | ESR1 (0.45) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL176020 | 0.64 | TAAR1 (0.59) | PTGS2ADRA2AKCNH2HSD17B10ALDH1A1 | |
| SCHEMBL25080869 | 0.62 | HTT (0.42) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL25851 | 0.62 | TAAR1 (0.57) | PTGS2ADRA2AKCNH2HSD17B10ALDH1A1 | |
| SCHEMBL272049 | 0.62 | TAAR1 (0.57) | PTGS2ADRA2AKCNH2HSD17B10ALDH1A1 | |
| SCHEMBL28940 | 0.62 | TAAR1 (0.57) | PTGS2ADRA2AKCNH2HSD17B10ALDH1A1 | |
| SCHEMBL21129395 | 0.62 | ALDH1A1 (0.37) | PTGS2CYP3A4ALDH1A1 | |
| SCHEMBL170953 | 0.62 | PTGS2 (0.50) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL1187598 | 0.61 | PTGS2 (0.52) | PTGS2CYP3A4ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563166-A | Thienyl- and furylpyrrole fungicidal agents | AMERICAN CYANAMID CO. (US) | 1996-10-08 | — | — | US | disclosed |
| US-5492925-A | PROTECTING PLANTS | AMERICAN CYANAMID COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5480902-A | Thienylpyrrole fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| CN-1107155-A | Thienyl- and furylpyrrole insecticidal and acaridical agents | AMERICAN CYANAMID CO (US) | 1995-08-23 | — | — | CN | disclosed |
| EP-0641794-A1 | Thienyl- and furylpyrrole derivatives, their preparation and their use as insecticides and acaricides | AMERICAN CYANAMID COMPANY (US) | 1995-03-08 | — | — | EP | disclosed |
| US-4473567-A | Substituted-imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid | SHIONOGI & CO., LTD. (JP) | 1984-09-25 | — | — | US | disclosed |
| US-4339575-A | PURIFICATION, CYCLIZATION WITH ALDEHYDE OR KETONE, CRYSTALLIZATION, HYDROLYSIS | SHIONOGI & CO., LTD. (JP) | 1982-07-13 | — | — | US | disclosed |