Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | BRAF | P15056 | 4/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11697723 | 0.93 | PGR (0.55) | HDAC3HDAC1HDAC2BRAFHDAC4 | |
| SCHEMBL28850376 | 0.84 | PGR (0.71) | HDAC3HDAC1HDAC2BRAFHDAC4 | |
| SCHEMBL11699565 | 0.82 | MEN1 (0.56) | HDAC3HDAC1HDAC2BRAFHDAC4 | |
| SCHEMBL359029 | 0.81 | MEN1 (0.68) | MEN1KMT2ARAB9ALMNAPOLB | |
| SCHEMBL1454287 | 0.81 | DEGS1 (0.53) | HDAC3HDAC1HDAC2BRAFHDAC4 | |
| SCHEMBL1856308 | 0.79 | SRD5A2 (0.50) | MEN1KMT2ARAB9APOLBTDP1 | |
| SCHEMBL30168224 | 0.79 | SRD5A2 (0.50) | MEN1KMT2ARAB9APOLBTDP1 | |
| SCHEMBL11650148 | 0.79 | PGR (0.81) | HDAC3HDAC1HDAC2BRAFHDAC4 | |
| SCHEMBL22192212 | 0.78 | PGR (0.57) | HDAC3HDAC1HDAC2BRAFHDAC4 | |
| SCHEMBL5148402 | 0.78 | MEN1 (0.60) | HDAC3HDAC1HDAC2BRAFHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5549965-A | MOLECULAR WEIGHT CONTROLLED BY NON-STOICHIOMETRIC ADDITION OF MONOMER UNITS; ENDS BLOCKED | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-27 | — | — | US | disclosed |
| EP-0496313-B1 | Non-woven reinforced with a meltbinder | HOECHST AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| EP-0496317-B1 | Prepreg and fibre reinforced composites therefrom | HOECHST AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| EP-0442399-B1 | Wholly aromatic polyamides, process for preparing them and moulded articles thereof | HOECHST AG (DE) | 1995-05-10 | — | — | EP | disclosed |
| EP-0496318-B1 | Aromatic copolyamids, method of preparation and shaped articles thereof | HOECHST AG (DE) | 1995-04-05 | — | — | EP | disclosed |
| US-5393601-A | Aromatic polyamide fibers; high strength filters, reinforcing materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-28 | — | — | US | disclosed |
| EP-0445673-B1 | Aromatic copolyamides, process for preparing them, and moulded articles therefrom | HOECHST AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| EP-0424860-B1 | Wholly aromatic polyamides, process for their preparation and products therefrom | HOECHST AG (DE) | 1993-12-01 | — | — | EP | disclosed |
| US-5235029-A | High strength polymers processable into fibers, membranes, films; soluble in organic amide solvent | HOECHST AG (DE) | 1993-08-10 | — | — | US | disclosed |
| EP-0364892-B1 | WHOLLY AROMATIC POLYAMIDES, PROCESS FOR PRODUCING THE SAME AND SHAPED ARTICLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-09 | — | — | EP | disclosed |
| EP-0424860-A2 | Wholly aromatic polyamides, process for their preparation and products therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-02 | — | — | EP | disclosed |
| US-4987217-A | Filaments, fibers, films, sheets, membranes having very high modulus of elasticity | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |
| US-4987215-A | Filaments, fibers, films, sheets, membranes of very high initial modulus | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |
| US-4987216-A | Filaments, fibers, films, sheets, membranes of very high initial modulus | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |
| EP-0199090-B1 | SHAPED ARTICLES OF AROMATIC COPOLYAMIDES, AND PROCESS FOR THEIR MANUFACTURE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-03 | — | — | EP | disclosed |
| EP-0364891-A2 | Wholly aromatic polyamides, process for producing the same and shaped articles | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0364893-A2 | Wholly aromatic polyamides, process for producing the same and shaped articles | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0364892-A2 | Wholly aromatic polyamides, process for producing the same and shaped articles | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | disclosed |
| US-4847354-A | Shaped structure of aromatic copolyamide from aromatic diamine mixture | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-11 | — | — | US | disclosed |
| EP-0199090-A2 | Shaped articles of aromatic copolyamides, and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-29 | — | — | EP | disclosed |