SCHEMBL8938032

SCHEMBL8938032

O=P(O)(O)C(Cc1ccccc1)c1ccc(Cl)c2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 11/20 0.65
LAP3 P28838 4/20 0.45
ANPEP P15144 2/20 0.45
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
ERAP1 Q9NZ08 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8938026 0.74 ACP3 (1.00) ACP3CYP1A2
SCHEMBL20587741 0.73 ACP3 (0.65) ACP3LAP3ANPEPERAP1
SCHEMBL28174182 0.72 ACP3 (1.00) ACP3LAP3ANPEP
SCHEMBL8824563 0.66 ACP3 (0.58) ACP3CYP1A2CYP2A6
SCHEMBL7158870 0.66 LAP3 (0.64) ACP3LAP3ANPEPCYP1A2ERAP1
SCHEMBL7742563 0.66 LAP3 (0.64) ACP3LAP3ANPEPCYP1A2ERAP1
SCHEMBL647559 0.65 CYP1A2 (0.52) CYP1A2CYP2A6
SCHEMBL10714585 0.64 LAP3 (0.62) ACP3LAP3ANPEPCYP1A2ERAP1
SCHEMBL27481841 0.64 LAP3 (0.62) ACP3LAP3ANPEPCYP1A2ERAP1
SCHEMBL777580 0.64 ACP3 (0.53) ACP3LAP3ANPEPPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5508273-A ARALKYLPHOSPHONATES FOR OSTEOPOROSIS ORTHO PHARMACEUTICAL CORPORATION (US) 1996-04-16 US disclosed