Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 7/20 | 0.87 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | PGK1 | P00558 | 1/20 | 0.49 |
| ▸ | PGK2 | P07205 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956963 | 0.82 | ACP3 (0.68) | ACP3PGK1PGK2CA12CA1 | |
| SCHEMBL30438454 | 0.77 | ACP3 (1.00) | ACP3HTR2AHTR2BHTR2CPGK1 | |
| SCHEMBL8938038 | 0.77 | ACP3 (0.90) | ACP3PGK1PGK2CA12CA1 | |
| SCHEMBL8938031 | 0.77 | ACP3 (1.00) | ACP3HTR2AHTR2BHTR2CPGK1 | |
| SCHEMBL9401137 | 0.75 | PGK1 (0.70) | ACP3PGK1PGK2CA12CA1 | |
| SCHEMBL8824569 | 0.75 | ACP3 (0.67) | ACP3PGK1PGK2CA12CA1 | |
| SCHEMBL28631469 | 0.75 | HTR2A (0.55) | ACP3HTR2AHTR2BHTR2CPNMT | |
| SCHEMBL9401118 | 0.74 | ACP3 (0.65) | ACP3PGK1PGK2CA12CA1 | |
| SCHEMBL12706099 | 0.74 | HTR2A (0.68) | ACP3HTR2AHTR2BHTR2CPNMT | |
| SCHEMBL14334811 | 0.73 | ACP3 (0.56) | ACP3HTR2AHTR2BHTR2CPGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |