Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 10/20 | 0.90 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | PNMT | P11086 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 2/20 | 0.51 |
| ▸ | PGK1 | P00558 | 3/20 | 0.47 |
| ▸ | PGK2 | P07205 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824569 | 0.84 | ACP3 (0.67) | ACP3CA12CA1MMP2PNMT | |
| SCHEMBL9401137 | 0.84 | PGK1 (0.70) | ACP3CA12CA1MMP2PNMT | |
| SCHEMBL9401118 | 0.83 | ACP3 (0.65) | ACP3CA12CA1MMP2PNMT | |
| SCHEMBL8956963 | 0.79 | ACP3 (0.68) | ACP3CA12CA1MMP2PNMT | |
| SCHEMBL8938034 | 0.77 | ACP3 (0.87) | ACP3CA12CA1MMP2PNMT | |
| SCHEMBL778799 | 0.76 | ACP3 (0.56) | ACP3CA12MMP2CES2PGK1 | |
| SCHEMBL4135956 | 0.75 | PNMT (0.65) | ACP3PNMTCES2IDO1TDO2 | |
| Phosphoric Acid SCHEMBL28200180 | 0.75 | PGK1 (0.61) | ACP3CA12CA1MMP2CES2 | |
| SCHEMBL4086256 | 0.74 | PNMT (0.58) | ACP3PNMTCES2IDO1TDO2 | |
| SCHEMBL5848264 | 0.73 | PNMT (0.53) | ACP3CA12CA1MMP2PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | claimed |
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |