Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938097 | 0.90 | ALOX15 (0.46) | ALOX15ALDH1A1KDM4EGAAHTT | |
| Hydrochloric Acid SCHEMBL8938103 | 0.85 | ALOX15 (0.48) | ALOX15ALDH1A1KDM4EGAAUSP2 | |
| SCHEMBL8938151 | 0.84 | ALOX15 (0.57) | ALOX15ALDH1A1KDM4EGAAADRB1 | |
| SCHEMBL8938156 | 0.84 | ALOX15 (0.57) | ALOX15ALDH1A1KDM4EGAAADRB1 | |
| SCHEMBL8938143 | 0.84 | ADRB3 (0.60) | ALOX15ADRB1 | |
| SCHEMBL8938126 | 0.84 | ALOX15 (0.53) | ALOX15ALDH1A1KDM4EGAAADRB1 | |
| SCHEMBL9188713 | 0.83 | ALOX15 (0.71) | ALOX15ALDH1A1KDM4EGAAADRB1 | |
| SCHEMBL9189156 | 0.83 | ALOX15 (0.71) | ALOX15ALDH1A1KDM4EGAAADRB1 | |
| Hydrochloric Acid SCHEMBL8938117 | 0.83 | ALOX15 (0.59) | ALOX15ALDH1A1KDM4EGAAADRB1 | |
| Hydrochloric Acid SCHEMBL8938120 | 0.83 | ALOX15 (0.59) | ALOX15ALDH1A1KDM4EGAAADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |