Sugi Predict

Sugi Predict / Compounds / Benzenesulfonamide

Benzenesulfonamide

Benzenesulfonamide

SCHEMBL8938299

CCOC(=O)c1cc2cc(Cl)ccc2n1S(=O)(=O)c1ccccc1.NS(=O)(=O)c1ccccc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NOD2 Q9HC29 4/20 0.70
▸ NOD1 Q9Y239 4/20 0.70
▸ PPARG P37231 8/20 0.53
▸ PPARA Q07869 6/20 0.53
▸ PPARD Q03181 5/20 0.53
▸ CHRNA7 P36544 6/20 0.44
▸ BCL2 P10415 1/20 0.43
▸ BID P55957 1/20 0.43
▸ MCL1 Q07820 1/20 0.43
▸ ACLY P53396 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2347003 0.95 NOD2 (0.78) NOD2NOD1PPARGPPARAPPARD
SCHEMBL8938264 0.93 NOD2 (0.64) NOD2NOD1PPARGPPARAPPARD
SCHEMBL8938381 0.89 NOD2 (0.64) NOD2NOD1PPARGPPARAPPARD
SCHEMBL22003860 0.85 NOD2 (0.69) NOD2NOD1PPARGPPARAPPARD
SCHEMBL16486105 0.82 NOD2 (0.58) NOD2NOD1PPARGPPARAPPARD
SCHEMBL3141535 0.82 NOD2 (0.69) NOD2NOD1PPARGPPARAPPARD
SCHEMBL2542152 0.82 NOD2 (0.86) NOD2NOD1BCL2BIDMCL1
SCHEMBL10003942 0.82 NOD2 (0.78) NOD2NOD1PPARGPPARAPPARD
SCHEMBL13114472 0.79 NOD2 (0.81) NOD2NOD1PPARGPPARDCHRNA7
SCHEMBL3837213 0.79 PPARG (0.61) NOD2NOD1PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5527819-A TREATING AIDS MERCK & CO., INC. (US) 1996-06-18 — — US disclosed
WO-1994019321-A1 INHIBITORS OF HIV REVERSE TRANSCRIPTASE MERCK & CO., INC. (US) 1994-09-01 — — WO disclosed