Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938556 | 0.86 | PREP (0.60) | PREPGRIN2BTSHRL3MBTL1KLK7 | |
| SCHEMBL8938606 | 0.86 | PREP (0.46) | PREPCTRB1KDM1ARCOR1 | |
| SCHEMBL8938518 | 0.85 | PKM (0.41) | — | |
| SCHEMBL8938544 | 0.84 | PREP (0.48) | PREPGRIN2BTSHRL3MBTL1KLK7 | |
| SCHEMBL8938432 | 0.80 | PREP (0.48) | PREPGRIN2BTSHRL3MBTL1KLK7 | |
| SCHEMBL8265528 | 0.78 | PREP (0.46) | PREPGRIN2BTSHRL3MBTL1KLK7 | |
| SCHEMBL10778848 | 0.75 | ACE (0.52) | PREP | |
| SCHEMBL7343528 | 0.75 | ACE (0.52) | PREP | |
| SCHEMBL10778850 | 0.75 | ACE (0.52) | PREP | |
| SCHEMBL8938625 | 0.72 | MEN1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | claimed |
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | disclosed |