Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938405 | 0.84 | PREP (0.46) | PREPGRIN2BKLK7KLK5CTRB1 | |
| SCHEMBL8938606 | 0.75 | PREP (0.46) | PREPCTRB1 | |
| SCHEMBL7343528 | 0.74 | ACE (0.52) | PREPKMT2A | |
| SCHEMBL10778848 | 0.74 | ACE (0.52) | PREPKMT2A | |
| SCHEMBL10778850 | 0.74 | ACE (0.52) | PREPKMT2A | |
| SCHEMBL3408366 | 0.70 | GRIN2B (0.57) | GRIN2BKMT2A | |
| SCHEMBL7394112 | 0.69 | POLB (0.46) | PREPTSHRL3MBTL1KMT2A | |
| SCHEMBL7302338 | 0.69 | PREP (0.67) | PREPKLK7KLK5CTRB1TSHR | |
| SCHEMBL7302343 | 0.69 | PREP (0.67) | PREPKLK7KLK5CTRB1TSHR | |
| SCHEMBL8938556 | 0.69 | PREP (0.60) | PREPGRIN2BKLK7KLK5CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | disclosed |