Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938246 | 0.81 | CNR1 (0.58) | NAMPT | |
| SCHEMBL8938285 | 0.80 | CNR1 (0.49) | — | |
| SCHEMBL9034050 | 0.79 | CNR1 (0.66) | CDK2 | |
| SCHEMBL9033484 | 0.79 | NAMPT (0.46) | NAMPT | |
| SCHEMBL8938277 | 0.78 | TUBB4A (0.47) | ALDH1A1KDM4ECDK2NAMPTMAPT | |
| SCHEMBL8938345 | 0.78 | CNR1 (0.49) | CDK2 | |
| SCHEMBL8938511 | 0.78 | TUBB4A (0.56) | ALDH1A1KDM4EMAPT | |
| SCHEMBL8938368 | 0.78 | TUBB4A (0.47) | ALDH1A1KDM4ENAMPTLMNASMN1; SMN2 | |
| SCHEMBL8938466 | 0.77 | CNR1 (0.49) | ALDH1A1KDM4E | |
| SCHEMBL8938481 | 0.77 | TUBB (0.53) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527819-A | TREATING AIDS | MERCK & CO., INC. (US) | 1996-06-18 | — | — | US | disclosed |
| WO-1994019321-A1 | INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1994-09-01 | — | — | WO | disclosed |