Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938565 | 1.00 | HRH3 (0.40) | HRH3FAAHCYP2D6CHRM2HTR1A | |
| SCHEMBL8938454 | 0.88 | HRH3 (0.54) | HRH3CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL8938542 | 0.82 | HRH3 (0.49) | HRH3CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL9259403 | 0.77 | FAAH (0.42) | HRH3FAAHCYP2D6CHRM2HTR1A | |
| SCHEMBL8938201 | 0.75 | HRH3 (0.53) | HRH3CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL8938514 | 0.75 | HRH3 (0.42) | HRH3 | |
| SCHEMBL8938621 | 0.75 | SIGMAR1 (0.41) | HRH3CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL8938361 | 0.75 | GBA1 (0.41) | HRH3CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL8938226 | 0.75 | HRH3 (0.40) | HRH3CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL8938310 | 0.75 | HRH3 (0.45) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534626-A | SELECTIVE MUSCARINIC RECEPTOR ANTAGONIST INTERMEDIATES | PFIZER INC. (US) | 1996-07-09 | — | — | US | disclosed |