Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938501 | 0.80 | MAP2K1 (0.40) | — | |
| SCHEMBL8939215 | 0.70 | HRH3 (0.38) | HRH3CYP2D6 | |
| SCHEMBL5865374 | 0.68 | HRH3 (0.47) | HRH3 | |
| SCHEMBL2570202 | 0.67 | MAP2K1 (0.62) | HRH3CYP2D6 | |
| SCHEMBL5865157 | 0.66 | SCD (0.48) | HRH3CYP2D6 | |
| Hydrochloric Acid SCHEMBL1397945 | 0.65 | HRH3 (0.53) | HRH3 | |
| SCHEMBL3639284 | 0.63 | HRH3 (0.42) | HRH3 | |
| SCHEMBL8934714 | 0.63 | HRH3 (0.39) | HRH3CYP2D6 | |
| SCHEMBL19575433 | 0.62 | HRH3 (0.41) | HRH3 | |
| SCHEMBL1397997 | 0.62 | HRH3 (0.50) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188117-B2 | Piperidinyl-substituted isoquinolone derivatives | SANOFI-AVENTIS (FR) | 2012-05-29 | — | — | US | disclosed |