Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938620 | 0.91 | PLA2G4A (0.48) | PKMPLA2G4ACES1MEN1NPC1 | |
| SCHEMBL8938439 | 0.89 | MEN1 (0.50) | PKMPLA2G4ACES1MEN1NPC1 | |
| SCHEMBL8938473 | 0.85 | PREP (0.56) | PKMPLA2G4ACES1MEN1NPC1 | |
| SCHEMBL8938526 | 0.83 | PLA2G4A (0.41) | PKMPLA2G4ACES1MEN1NPC1 | |
| SCHEMBL8938442 | 0.82 | PKM (0.42) | PKMPLA2G4ACES1MEN1NPC1 | |
| SCHEMBL8938468 | 0.82 | PREP (0.43) | PKMPLA2G4ACES1MEN1NPC1 | |
| SCHEMBL8938518 | 0.82 | PKM (0.41) | PKMPLA2G4ACES1MEN1NPC1 | |
| SCHEMBL10517561 | 0.76 | PREP (0.68) | NPC1PREP | |
| SCHEMBL10517569 | 0.76 | PREP (0.68) | NPC1PREP | |
| SCHEMBL7372462 | 0.76 | MEN1 (0.50) | MEN1NPC1RAB9AKMT2APREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | claimed |
| US-5547978-A | ENDOPEPTIDASE INHIBITORS | MEIJI SEIKA KAISHA, LTD. (JP) | 1996-08-20 | — | — | US | disclosed |